EXPLORING THE PROGRESSION OF DRUG DEPENDENCE IN A METHAMPHETAMINE SELF-ADMINISTRATION RAT MODEL THROUGH TARGETED AND NON-TARGETED METABOLOMICS ANALYSES

Abstract Persistent neurochemical and biological disturbances resulting from repeated cycles of drug reward, withdrawal, and relapse contribute to drug dependence.Methamphetamine (MA) is a psychostimulant with substantial abuse potential and neurotoxic effects, primarily affecting monoamine neurotransmitter systems in the brain.In this study, we ai

The effect of outside influences on judicial decision-making has a long and storied history.However, the impact of celebrity status as an outside influence 5.11 flex shotgun ammo pouch on judicial decision-making has received very little attention in the literature.I examine 303 celebrity verdicts from 1998 to 2010 to shed light on whether celebrit

This study involves the cradle-to-gate life cycle assessment of tomato paste production in Turkey.All the data was obtained from a large-scale production company located in north-west Turkey in 2020.CCaLC software with Ecoinvent2 database alongside CML2001 method was used for the analysis and the following impacts were taken into account: acidifica

Background: While the proliferation of social media is hailed for increasing corporate business networking and competitiveness, this claim has not been sufficiently tested in tourism small, medium and micro enterprises (SMMEs) in African emerging economies where traditional communication modes tend to dominate.Setting: This study investigates the u